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A leap forward of bio-medical technology that surpasses the traditional bio-tech

The National Applied Research Laboratories (NARL) recently announced its successful invention of "An ultra rapid diagnostic chip for detection of pathogen form human blood" that enables doctors and medical technologists to determine the acute septicemia and bacteremia just within 5 minutes.

The 5-minute test technology allows a fast detection of the pathogenic bacteria of acute septicemia and bacteremia! The "An ultra rapid diagnostic chip for detection of pathogen form human blood", invented by NARL-NDL.

Since the pathogenic bacteria are allowed to be detected and identified within the golden hour, accurate medications are possible and expected to effectively lower the death rate and reduce the problem on antibiotics abuse.

The "An ultra rapid diagnostic chip for detection of pathogen form human blood", invented by the southern unit of the National Nano Device Laboratories (NDL) of the NARL. This chip can assist doctors to diagnose whole bacteria from human blood in five minutes without any expensive and time-consuming processes/measurements, such as the antibody modification, biochemical reaction and the DNA measurement that needs to disrupt the cell.

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In fact, both the traditional blood bacteria culture and the biotech tests are time-consuming and complicated that only professionals are capable to do. Given the lack of a fast way to detect pathogenic bacteria, the NARL-NDL tried to accelerate and simplify the operation and detection procedures.

It planned to have the index bacteria simultaneously isolated and concentrated within 3 minutes just by using a low voltage source, which would result in a high density bacteria aggregator. Then, on-chip bacteria fingerprint spectrum analysis, comparison and identification of the concentrated and isolated bacteria would be carried out less than 2 minutes. In the end, the two processes could be completed just within 5 minutes.

Given such an inexpensive, easy-to-use and extensively-applied technology, the timely report of the detected bacteria and specific protein contained in blood could greatly help doctors diagnose and medicate accurately. The death rate could therefore be significantly lowered, and patients are allowed to suffer less pain. What’s better, it is a semi-automatic technology that could be easily operated under instructions and free of biotech procedures.

Such invention made by the NARL-NDL could significantly reduce the time and cost of many medical detections. In addition, the future development of the technology would go toward the research of the portable diagnostic devices for rapid screenings and tests in field.

So far, it has attracted several companies to look for the possibility of technology transfers. The possible industry-research alliance is supposed to work out more applications to the fast tests on biomolecule and virus, as well as on virus infection and specific protein in blood. Besides, more substantial breaking medical achievements, such as the enhancing the sensitivity for molecular detections and reducing the blood cell disturbance for blood glucose test, are also expected to be made to boost the competitiveness of Taiwan’s bio-medical industries.